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IL-18 Recombinant Protein

CAT: 0223-91-943Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-943Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon- gamma (IFN- gamma) or type II interferon that plays an important role in activating the macrophages or other cells.
CAS Number
9000-83-3
NCBI Gene ID
3606
Swiss Prot
Q14116
Accession Number
Q14116
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Obesity, Inflammasomes
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
23.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interleukin 18
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-18, Iboctadekin, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, GIF, IL-18, IL-1g, IL1F4, MGC12320, IL-1F4
Species
Human
Physical Properties
Lyophilized

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