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IL-1 beta Recombinant Protein

CAT: 0223-91-032Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-032Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-1 (IL-1) designates two proteins, IL-1 alpha and IL-1 beta , which are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1 beta , designated interleukin 1 beta -converting enzyme (ICE), has been described. Mature human and mouse IL-1 beta share approximately 75% amino acid sequence identity and human IL-1 beta has been found to be active on murine cell lines.
CAS Number
9000-83-3
NCBI Gene ID
16176
Swiss Prot
P10749
Accession Number
P10749
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology, Inflammasomes
Buffer
Lyophilized from a 0.2 um filtered solution of 50mM TrisHCl, 50mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
17.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interleukin 1 beta
NCBI Organism
Mus musculus
Other Product Names
Interleukin-1 Beta, IL-1 Beta, Il1b, IL-1F2, IL-1b
Species
Mouse
Physical Properties
Lyophilized

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