IL-36 beta Recombinant Protein

• Background:

  IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

• NCBI Gene ID:

  69677

• Swiss Prot:

  Q9NZH7

• Accession Number:

  Q9D6Z6

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines

• Concentration:

  0.1mg/ml after reconstitution.

• Buffer:

  Contains PBS + 0.5% Trehalose. Reconstitute with 100 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Interleukin 1 family, member 8

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Interleukin-36beta, Interleukin-1 Family Member 8, IL-1F8

• Species:

  Mouse

• Protein ID:

  25008591

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3