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IL-24 Recombinant Protein

CAT: 0223-90-527Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0223-90-527Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. It is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer. IL-24 has antiproliferative properties is inhibiting angiogenesis and may contribute to terminal cell differentiation.
CAS Number
9000-83-3
NCBI Gene ID
11009
Swiss Prot
Q61790
Accession Number
AAH09681
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Cancer, Immunology
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 24
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-24, MDA7, ST16
Species
Human
Protein ID
16307185
Physical Properties
Lyophilized

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