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IL-1beta Recombinant Protein

CAT: 0223-40-598Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-598Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1β is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
CAS Number
9000-83-3
NCBI Gene ID
16176
Swiss Prot
P10749
Accession Number
NP_032387.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology, Inflammasomes
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-1beta recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-1beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-1beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 1 beta
NCBI Organism
Mus musculus
Other Product Names
Il-1b, IL-1beta, Interleukin-1 beta, IL-1 beta
Species
Human
Protein ID
6680415
Physical Properties
Lyophilized

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