IL-12 Recombinant Protein

• Background:

  IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma) and tumor necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

• NCBI Gene ID:

  16160

• Swiss Prot:

  P43432 , NP032377

• Accession Number:

  P43432 , NP032377

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology, Innate Immunity

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  57.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interleukin 12b

• NCBI Organism:

  Mus musculus

• Other Product Names:

  IL-12, Interleukin 12, Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3