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IL-12 Recombinant Protein

CAT: 0223-92-631Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-631Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma) and tumor necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.
CAS Number
9000-83-3
NCBI Gene ID
16160
Swiss Prot
P43432 , NP032377
Accession Number
P43432 , NP032377
Tag
Tag Free
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology, Innate Immunity
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
57.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interleukin 12b
NCBI Organism
Mus musculus
Other Product Names
IL-12, Interleukin 12, Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell
Species
Mouse
Physical Properties
Lyophilized

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