Hepatoma-Derived Growth Factor Recombinant Protein

• Background:

  Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.

• NCBI Gene ID:

  3068

• Swiss Prot:

  P51858

• Accession Number:

  P51858

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Tris, 1mM DTT, 1mM EDTA, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  12.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Hepatoma-derived growth factor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Hepatoma-Derived Growth Factor, HDGF, High Mobility Group Protein 1-Kike 2, HMG-1L2, HMG1L2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3