Hepatocyte growth factor Recombinant Protein

• Background:

  Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. It belongs to the peptidase S1 family and Plasminogen subfamily, contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.

• NCBI Gene ID:

  3082

• Swiss Prot:

  P14210

• Accession Number:

  P14210

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction, Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  80.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Hepatocyte growth factor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Hepatocyte growth factor, HPTA, HGF, SF, Scatter factor, Hepatopoietin-A

• Species:

  Human

• Protein ID:

  524552373

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3