GCN5 highly active Recombinant Protein

• Background:

  GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.

• NCBI Gene ID:

  2648

• Swiss Prot:

  O88430

• Accession Number:

  Q92830

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  Sf21 cells

• Field of Research:

  Other

• Concentration:

  Lot dependent (0.2-0.5mg/ml)

• Purity:

  >95% (SDS-PAGE)

• Buffer:

  In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -80˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  K (lysine) acetyltransferase 2A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GCN5L2, Histone Acetyltransferase GCN5, Histone Acetyltransferase KAT2A, Lysine Acetyltransferase 2A, STAF97

• Species:

  Human

• Protein ID:

  209572743

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3