FLT3 Ligand Recombinant Protein

• Background:

  FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells) ) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.

• NCBI Gene ID:

  2323

• Swiss Prot:

  P25311

• Accession Number:

  P49771

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Signal Transduction

• Concentration:

  1mg/ml

• Buffer:

  In PBS (sterile) .

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Fms-related tyrosine kinase 3 ligand

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FMS-like Tyrosine Kinase 3 Ligand

• Species:

  Human, Mouse

• Protein ID:

  1706818

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3