DFF45 Recombinant Protein

• Background :

  DNA Fragmentation Factor Subunit Alpha (DFFA) . DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

• NCBI Gene ID :

  1676

• Swiss Prot :

  O00273

• Accession Number :

  O00273

• Tag :

  N-6 His tag

• Type :

  Recombinant Proteins

• Source :

  E. coli

• Field of Research :

  Apoptosis

• Buffer :

  Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions :

  Dry Ice

• Calculated Molecular Weight :

  38.7 kD

• Applications Notes :

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name :

  DNA fragmentation factor subunit alpha

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFF-45, Inhibitor of CAD, ICAD, DFFA, DFF1, DFF45, H13

• Species :

  Human

• Physical Properties :

  Liquid

• CAS Number :

  9000-83-3