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DFF45 Recombinant Protein

CAT: 0223-92-051Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-051Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DNA Fragmentation Factor Subunit Alpha (DFFA) . DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
CAS Number
9000-83-3
NCBI Gene ID
1676
Swiss Prot
O00273
Accession Number
O00273
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
38.7 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
DNA fragmentation factor subunit alpha
NCBI Organism
Homo sapiens
Other Product Names
DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFF-45, Inhibitor of CAD, ICAD, DFFA, DFF1, DFF45, H13
Species
Human
Physical Properties
Liquid

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