Autophagy protein 4C Recombinant Protein

• Background:

  Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE) -conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.

• NCBI Gene ID:

  84938

• Swiss Prot:

  Q96DT6

• Accession Number:

  Q96DT6

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Autophagy

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  53.56 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Autophagy related 4C cysteine peptidase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cysteine Protease ATG4C, AUT-Like 3 Cysteine Endopeptidase, Autophagin-3, Autophagy-Related Cysteine Endopeptidase 3, Autophagy-Related Protein 4 homolog C, ATG4C, APG4C, AUTL1, AUTL3

• Species:

  Human

• Protein ID:

  530363504

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3