CD40 Recombinant Protein

CAT: 0223-91-887Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-887Size:0.05 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
CAS Number
9000-83-3
NCBI Gene ID
958
Swiss Prot
P25942
Accession Number
P25942
Tag
C-Fc-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Apoptosis, Immunology, Neuroscience, Signal Transduction, Stem Cell, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
46.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD40 molecule
NCBI Organism
Homo sapiens
Other Product Names
Tumor Necrosis Factor Receptor Superfamily member 5, B-Cell Surface Antigen CD40, Bp50, CD40L Receptor, CDw40, CD40, TNFRSF5
Species
Human
Physical Properties
Lyophilized

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