CD300a Recombinant Protein

• Background :

  CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d) . It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.

• NCBI Gene ID :

  11314

• Swiss Prot :

  Q9UGN4

• Accession Number :

  Q9UGN4

• Tag :

  C-Fc-6 His tag

• Type :

  Recombinant Proteins

• Source :

  Human Cells

• Buffer :

  Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NACl,5% Trehalose, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions :

  Room Temp

• Calculated Molecular Weight :

  45.4 kD

• Applications Notes :

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name :

  CD300a molecule

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CMRF35-like molecule 8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor, LMIR1

• Species :

  Human

• Physical Properties :

  Lyophilized

• CAS Number :

  9000-83-3