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CD28H Recombinant Protein

CAT: 0223-96-844Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-844Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1, is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue, the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
CAS Number
9000-83-3
NCBI Gene ID
126259
Swiss Prot
Q96BF3-1
Accession Number
AAH15655.1
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
40.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Transmembrane and immunoglobulin domain containing 2
NCBI Organism
Homo sapiens
Background Reference 01
Zhu, Y. et al., 2013, Nat. Commun., 4:2043.
Background Reference 02
Rahimi, N. et al., 2012, Mol. Biol. Cell., 23 (9) :1646-1656.
Background Reference 03
Kaneko, T. et al., 2008, Front. Biosci., 13:4938.
Other Product Names
TMIGD2, IGPR1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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