CD177 Recombinant Protein

CAT: 0223-91-398Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-398Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI) -linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors, and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI) -linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
CAS Number
9000-83-3
NCBI Gene ID
57126
Swiss Prot
Q8N6Q3
Accession Number
Q8N6Q3
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
42.33 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD177 molecule
NCBI Organism
Homo sapiens
Other Product Names
CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA-2a, NB1 Glycoprotein, NB1 GP, Polycythemia Rubra Vera Protein 1, PRV-1, CD177, NB1, PRV1
Species
Human
Protein ID
929654682
Physical Properties
Lyophilized

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