CCL11 Recombinant Protein

• Background:

  C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

• NCBI Gene ID:

  6356

• Swiss Prot:

  P51671

• Accession Number:

  P51671

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines, Immunology, Infectious Disease

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  8.56 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  C-C motif chemokine ligand 11

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Eotaxin, C-C Motif Chemokine 11, Eosinophil Chemotactic Protein, Small-Inducible Cytokine A11, CCL11, SCYA11

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3