Products for Research Use Only

CCL11 Recombinant Protein

CAT: 0223-92-100Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-100Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
CAS Number
9000-83-3
NCBI Gene ID
6356
Swiss Prot
P51671
Accession Number
P51671
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology, Infectious Disease
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
8.56 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
C-C motif chemokine ligand 11
NCBI Organism
Homo sapiens
Other Product Names
Eotaxin, C-C Motif Chemokine 11, Eosinophil Chemotactic Protein, Small-Inducible Cytokine A11, CCL11, SCYA11
Species
Human
Physical Properties
Lyophilized