CD52 Recombinant Protein

• Background:

  CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs) .ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

• NCBI Gene ID:

  1043

• Swiss Prot:

  P31358

• Accession Number:

  NP_001794.2

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Chemokines & Cytokines, Immunology, Other

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  27.9 kDa

• Applications Notes:

  This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• NCBI Official Name:

  CD52 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhao Y., et al., 2017 , Immunogenetics.

• Background Reference 02:

  Hersh C., et al., 2014, Immunotherapy. 6 (3) :249-59.

• Background Reference 03:

  Zinzani PL., et al., 2012, Leuk Lymphoma. 53 (5) :789-9

• Other Product Names:

  CDW52, HE5, CD52, CAMPATH-1 antigen

• Tested Applications:

  ELISA, WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3