Beta-Defensin 1 Recombinant Protein

• Background:

  Beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.

• NCBI Gene ID:

  1672

• Swiss Prot:

  P60022

• Accession Number:

  P60022

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  5.07 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Defensin beta 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3