TACI Recombinant Protein

• Background:

  B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL) and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor (BAFF) of ligands and a proliferation inducing ligand (APRIL), which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils. TNFRSF13B, the gene, which encodes TACI is mutated in nearly 10% of patients with common variable immune deficiency (CVID), an antibody deficiency syndrome characterized by loss of memory B cells and plasma cells.

• NCBI Gene ID:

  23495

• Swiss Prot:

  O35305

• Accession Number:

  O14836

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Apoptosis, Immunology

• Concentration:

  1mg/ml after reconstitution.

• Buffer:

  Contains PBS. Reconstitute with 50 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily, member 13B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TNFRSF 13B, Tumor Necrosis Factor Receptor Superfamily Member 13B, Transmembrane Activator and CAML interactor, CD267

• Species:

  Human, Mouse

• Protein ID:

  6912694

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3