BAFFR Recombinant Protein

• Background:

  BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE) . Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

• NCBI Gene ID:

  115650

• Swiss Prot:

  Q96RJ3-1

• Accession Number:

  Q96RJ3-1

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Other

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  33.2 kDa

• Applications Notes:

  This recombinant protein can be used for E, WB. For research use only.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily member 13C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Thompson JS., et al.,2001, Science, 293 (5537) : 2108-2111.

• Background Reference 02:

  Mbrose CM., 2003, Journal of Biological Regulators and Homeostatic Agents, 16 (3) : 211-213.

• Background Reference 03:

  Treml LS., et al., 2006, Seminars in Immunology, 18 (5) : 297-304.

• Other Product Names:

  BAFFR, TNFRSF13C, BAFF-R, BROMIX, CD268, CVID4, prolixin

• Tested Applications:

  ELISA, WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3