Vaccinia Virus B18R Recombinant Protein

• Background:

  B18R is a type I interferon (IFN) -binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.

• NCBI Gene ID:

  3707577

• Swiss Prot:

  P25213

• Accession Number:

  P25213

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Infectious Disease

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  40.3 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Soluble interferon alpha/beta receptor B18

• NCBI Organism:

  Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR) )

• Background Reference 01:

  Alcami A., et al., 2000, J. Virol. 74:11230-11239.

• Background Reference 02:

  Waibler Z., et al., 2009, J. Virol. 83:1563-1571.

• Other Product Names:

  B18R

• Tested Applications:

  ELISA, WB

• Species:

  Vaccinia Virus

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3