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AG-2 Recombinant Protein

CAT: 0223-91-380Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-380Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175) . Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
CAS Number
9000-83-3
NCBI Gene ID
10551
Swiss Prot
O95994
Accession Number
O95994
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Obesity
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris,200mM NaCl,10％Glycerol, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
18.85 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Anterior gradient 2, protein disulphide isomerase family member
NCBI Organism
Homo sapiens
Other Product Names
Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2
Species
Human
Protein ID
530384410
Physical Properties
Liquid

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