Angiopoietin-2 Recombinant Protein

• Background:

  Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.

• NCBI Gene ID:

  285

• Swiss Prot:

  P05230

• Accession Number:

  O15123

• Tag:

  DDDDK Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Cell Cycle

• Concentration:

  0.1 mg /ml after reconstitution.

• Buffer:

  Contains PBS with trehalose and Brij35. Reconstitute with 100 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Angiopoietin 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Ang-2, Ang2, Angpt2

• Species:

  Human, Mouse

• Protein ID:

  4557315

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3