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Macranthoin G

CAT: 0804-HY-N8453-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8453-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macranthoin G is an inhibitor of p38 MAPK. Macranthoin G protects the cytotoxicity induced by Aβ or hydrogen peroxide in neuronal cells by downregulating p38 MAPK. Macranthoin G can used in study Alzheimer’s Disease[1].
CAS Number
159934-13-1
Product Name Alternative
Methyl 3,5-dicaffeoyl quinic acid
UNSPSC
12352005
Target
P38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/macranthoin-g.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)[C@@](C1)(O)C[C@@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)[C@@H]1OC(/C=C/C3=CC(O)=C(O)C=C3)=O
Molecular Formula
C26H26O12
Molecular Weight
530.48
References & Citations
[1]Lee JK, et al. Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease. Molecules. 2017 Aug 2;22 (8) :1287.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported