IMP2-IN-2

IMP2-IN-2

• CAS Number: 1448353-39-6
• UNSPSC Description: IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer[1].
• Target Antigen: Insulin Receptor
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/imp2-in-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=C(NC(N(CC)CC2=CC=CC=C2)=O)C=C(C3=CC=C(C(F)(F)F)C=C3)S1)O
• Molecular Weight: 448.46
• References & Citations: [1]Dahlem C, et, al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17(2):361-375.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported