IMP2-IN-2

• Description :

  IMP2-IN-2 (compound 6) is a potent and selective IMP2 inhibitor, with IC50s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer[1].

• UNSPSC :

  12352005

• Target :

  Insulin Receptor

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/imp2-in-2.html

• Concentration :

  10mM

• Purity :

  99.93

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=C(NC(N(CC)CC2=CC=CC=C2)=O)C=C(C3=CC=C(C(F)(F)F)C=C3)S1)O

• Molecular Formula :

  C22H19F3N2O3S

• Molecular Weight :

  448.46

• References & Citations :

  [1]Dahlem C, et, al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022 Feb 18;17 (2) :361-375.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1448353-39-6]