Beta-Eudesmol
CAT:
804-HY-N6018-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Beta-Eudesmol
- CAS Number: 473-15-4
- UNSPSC Description: Beta-Eudesmol has anticancer and anti-inflammatory activities. Beta-Eudesmol can induce apoptosis. Beta-Eudesmol is a neostigmine antagonist. Beta-Eudesmol can antagonize neostigmine-induced neuromuscular failure. Beta-Eudesmol can be used in the study of sepsis diseases. Beta-Eudesmol is a sesquiterpene-like compound that can be extracted from the rhizome of Atractylodes lancea[1][2][3][4].
- Target Antigen: Caspase; Reactive Oxygen Species; SOD; TNF Receptor
- Type: Natural Products
- Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/beta-eudesmol.html
- Purity: 96.54
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
- Smiles: C[C@]12[C@@](C(CCC2)=C)([H])C[C@H](C(C)(O)C)CC1
- Molecular Weight: 222.37
- References & Citations: [1]Ma EL,et al. Beta-eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferation. J Asian Nat Prod Res. 2008 Jan-Feb;10(1-2):159-67.|[2] Xu Q, et al. Protective effects of β-eudesmol against septic liver injury via inhibition of NF-κB signaling[J]. Tropical Journal of Pharmaceutical Research, 2022, 21(6): 1183-1188.|[3]Chiou LC, et al. Antagonism by beta-eudesmol of neostigmine-induced neuromuscular failure in mouse diaphragms. Eur J Pharmacol. 1992 Jun 5;216(2):199-206.|[4]Hoang D M, et al. Eudesmols induce apoptosis through release of cytochrome c in HL-60 cells[J]. Natural Product Sciences, 2010, 16(2): 88-92.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported