Beta-Eudesmol

• UNSPSC Description:

  Beta-Eudesmol has anticancer and anti-inflammatory activities. Beta-Eudesmol can induce apoptosis. Beta-Eudesmol is a neostigmine antagonist. Beta-Eudesmol can antagonize neostigmine-induced neuromuscular failure. Beta-Eudesmol can be used in the study of sepsis diseases. Beta-Eudesmol is a sesquiterpene-like compound that can be extracted from the rhizome of Atractylodes lancea[1][2][3][4].

• Target Antigen:

  Caspase; Reactive Oxygen Species; SOD; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/beta-eudesmol.html

• Purity:

  96.54

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL

• Smiles:

  C[C@]12[C@@](C(CCC2)=C)([H])C[C@H](C(C)(O)C)CC1

• Molecular Weight:

  222.37

• References & Citations:

  [1]Ma EL,et al. Beta-eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferation. J Asian Nat Prod Res. 2008 Jan-Feb;10(1-2):159-67.|[2] Xu Q, et al. Protective effects of β-eudesmol against septic liver injury via inhibition of NF-κB signaling[J]. Tropical Journal of Pharmaceutical Research, 2022, 21(6): 1183-1188.|[3]Chiou LC, et al. Antagonism by beta-eudesmol of neostigmine-induced neuromuscular failure in mouse diaphragms. Eur J Pharmacol. 1992 Jun 5;216(2):199-206.|[4]Hoang D M, et al. Eudesmols induce apoptosis through release of cytochrome c in HL-60 cells[J]. Natural Product Sciences, 2010, 16(2): 88-92.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  473-15-4