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Dnp-PYAYWMR

CAT: 0804-HY-P2089Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P2089Size:1 Each
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Description
Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm) . After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].
CAS Number
135662-06-5
UNSPSC
12352209
Target
MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dnp-pyaywmr.html
Solubility
10 mM in DMSO
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCSC)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C)NC([C@H](CC4=CC=C(O)C=C4)NC([C@H]5N(C6=CC=C([N+]([O-])=O)C=C6[N+]([O-])=O)CCC5)=O)=O)=O)=O)=O)=O
Molecular Formula
C54H65N13O14S
Molecular Weight
1152.24
References & Citations
[1]Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11 (20) :6009-6018.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported