Products for Research Use Only
RegisterLogin

Diosgenin (Standard)

CAT: 0804-HY-N0177R-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0177R-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Diosgenin (Standard) is the analytical standard of Diosgenin. This product is intended for research and analytical applications. Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway[1]. Diosgenin is an exogenous activator of Pdia3/ERp57[2]. Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression[5].
CAS Number
512-04-9
UNSPSC
12352005
Target
MicroRNA; Reference Standards; STAT
Type
Reference Standards
Related Pathways
Epigenetics; JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diosgenin-standard.html
Smiles
O[C@]1([H])CC2=CC[C@]3([H])[C@@](CC[C@@]4(C)[C@@]3([H])C[C@@]5([H])[C@]4([H])[C@@](C)([H])[C@@]6(CC[C@@]([H])(C)CO6)O5)([H])[C@@]2(C)CC1
Molecular Formula
C27H42O3
Molecular Weight
414.62
References & Citations
[1]Jeremy E. Chojnacki, et al. Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer’s disease. Bioorganic & Medicinal Chemistry, 23 (2015) 7324–7331|[2]Li F, et al. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett. 2010 Jun 28;292 (2) :197-207.|[3]Wang X, et al. Effect of diosgenin on metabolic dysfunction: Role of ERβ in the regulation of PPARγ. Toxicol Appl Pharmacol. 2015 Dec 1;289 (2) :286-96.|[4]Tohda C, et al. Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice. Sci Rep. 2012;2:535.|[5]Yun-cheng Lv, et al. Diosgenin Inhibits Atherosclerosis via Suppressing the MiR-19b-induced Downregulation of ATP-binding Cassette Transporter A1. Atherosclerosis, 2014, 240 (1), 80-89.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-N0730R-01Diosgenin glucoside (Standard)
HY-N0177-01Diosgenin
HY-N11617Diosgenin palmitate
HY-137179-01Glyco-diosgenin
HY-N0730-01Diosgenin glucoside
HY-N0125R-01Diosmetin (Standard)
HY-W145687Diosgenin-3-O-β-D-sodium glucuronide
HY-N12002-01Diosgenin-3-O-rhamnosyl (1→2) [glucosyl (1→6) ]glucoside
HY-N6879RDiosMetin 7-O-β-D-Glucuronide (Standard)
HY-P2274RArgifin (Standard)

Alternative Products

CatalogName
TB0204-1000Diosgenin

Popular Products