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Rotundic acid

CAT: 0804-HY-N2217-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2217-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rotundic acid, a triterpenoid obtained from Ilex rotunda Thunb., induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].
CAS Number
20137-37-5
UNSPSC
12352211
Target
Akt; Apoptosis; mTOR; p38 MAPK
Type
Natural Products
Related Pathways
Apoptosis; MAPK/ERK Pathway; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/rotundic-acid.html
Purity
99.41
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]1(CO)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
Molecular Formula
C30H48O5
Molecular Weight
488.70
References & Citations
[1]Roy G, et al. Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways. Front Oncol. 2019 Jun 26;9:545.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
MTOR; p38 MAPK

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