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Miptenalimab

CAT: 0804-HY-P99736-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99736-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3) . Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II[1].
CAS Number
2249882-55-9
Product Name Alternative
BI-754111
UNSPSC
12352203
Target
LAG-3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/miptenalimab.html
Purity
98.81
Solubility
10 mM in DMSO
Smiles
[Miptenalimab]
Molecular Weight
(145.84 kDa)
References & Citations
[1]Zettl M, et al. Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses. Oncoimmunology. 2022 Jun 16;11 (1) :2080328.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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