Practolol

Practolol

• CAS Number: 6673-35-4
• UNSPSC Description: Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].
• Target Antigen: Adrenergic Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/practolol.html
• Purity: 99.78
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC(NC1=CC=C(OCC(O)CNC(C)C)C=C1)=O
• Molecular Weight: 266.34
• References & Citations: [1]Iakovidis D, et, al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68(4):677-85.|[2]Adashi EY, et, al. Stimulation of beta 2-adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology. 1981 Jun;108(6):2170-8.|[3]Marshall RJ, et, al. Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. Br J Pharmacol. 1976 Jun;57(2):295-303.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported