Products for Research Use Only
RegisterLogin

3-Isomangostin

CAT: 0804-HY-N6845-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N6845-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents[1].
CAS Number
19275-46-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-isomangostin.html
Purity
99.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(C)=C\CC1=C2C(OC3=C(C(O)=C4C(OC(C)(C)CC4)=C3)C2=O)=CC(O)=C1OC
Molecular Formula
C24H26O6
Molecular Weight
410.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Yokoyama T, et al. Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening. Eur J Med Chem. 2019 Apr 1;167:153-160.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N83621-Isomangostin
HY-W081226-013,3,3-Trifluoropropionyl chloride
HY-W127810-013,3',3''-Nitrilotripropionic Acid
HY-W4403031,1',3,3,3',3'-Hexamethylindotricarbocyanine (perchlorate)
HY-D1075-011,1',3,3,3',3'-Hexamethylindodicarbocyanine (iodide)
HY-W1146693- (3- (3-Ethoxy-3-oxopropoxy) propoxy) propanoicacid
HY-178928KV1.3-IN-3
HY-176547FGFR2/3-IN-3
HY-79034-013,3-Dimethylcyclohexanone
HY-131942SFTX-3.3

Alternative Products

CatalogName
N2215-203-isomangostin
TN29543-Isomangostin hydrate
TN29553-Isomangostin hydrate formate
TN2546-011-Isomangostin
T4064-011-Isomangostin hydrate

Popular Products