Niranthin (Standard)

Niranthin (Standard)

• CAS Number: 50656-77-4
• UNSPSC Description: Niranthin (Standard) is the analytical standard of Niranthin. This product is intended for research and analytical applications. Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.
• Target Antigen: Parasite; Topoisomerase
• Type: Reference Standards
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/niranthin-standard.html
• Smiles: COC1=C2C(OCO2)=CC(C[C@H](COC)[C@@H](COC)CC3=CC(OC)=C(C=C3)OC)=C1
• Molecular Weight: 432.51
• References & Citations: [1]Sayan Chowdhury, et al. The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice. EMBO Mol Med. 2012 Oct;4(10):1126-43.
• Shipping Conditions: Room temperature