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Kayaflavone

CAT: 0804-HY-N9861Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N9861Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kayaflavone is an amentoflavone type biflavonoid. Kayaflavone has an inhibitory activity against amyloid-β42 cytotoxicity in PC-12 cells with an EC50 value of 5.29 μΜ. Kayaflavone is promising for research of Alzheimer’s disease[1].
CAS Number
481-45-8
UNSPSC
12352005
Target
Amyloid-β
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kayaflavone.html
Smiles
O=C1C=C(C2=CC(C3=C(C=C(C4=C3OC(C5=CC=C(OC)C=C5)=CC4=O)O)OC)=C(OC)C=C2)OC6=C1C(O)=CC(O)=C6
Molecular Formula
C33H24O10
Molecular Weight
580.54
References & Citations
[1]Sasaki H, et al. Inhibitory activities of biflavonoids against amyloid-β peptide 42 cytotoxicity in PC-12 cells. Bioorg Med Chem Lett. 2015 Jul 15;25 (14) :2831-3.|[2]Sun CM, et al. Selective cytotoxicity of ginkgetin from Selaginella moellendorffii. J Nat Prod. 1997 Apr;60 (4) :382-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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