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FR179642

CAT: 0804-HY-129077-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129077-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin[1]. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379[2].
CAS Number
168110-44-9
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fr179642.html
Purity
99.84
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@](NC([C@](NC([C@@](C[C@H]1O)([H])N(C1)C2=O)=O)([H])[C@H](O)[C@H](C(C=C3)=CC(O[S](=O)(O)=O)=C3O)O)=O)([H])[C@H](O)CC(N)=O)N(C[C@@H]4C)[C@@](C(N[C@@H]([C@@H](C[C@@H](C(N[C@@]2([H])[C@H](O)C)=O)N)O)O)=O)([H])[C@H]4O
Molecular Formula
C35H52N8O20S
Molecular Weight
936.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Satoshi Ueda, et al. Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907. J Antibiot (Tokyo) |[2]M Tomishima, et al. FK463, a novel water-soluble echinocandin lipopeptide: synthesis and antifungal activity. J Antibiot (Tokyo) |[3]Jiang X, et al., A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein Families. Mar Drugs. 2024 May 7;22 (5) :212.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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