[Phe2]-TRH

CAT: 0804-HY-P3962Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P3962Size:1 Each
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Description
[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin[1].
CAS Number
[34783-35-2]
UNSPSC
12352209
Target
Thyroid Hormone Receptor
Type
Peptides
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/phe2-trh.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CCC(N1)=O)N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N)=O)=O
Molecular Formula
C19H24N4O4
Molecular Weight
372.42
References & Citations
[1]Eckle E, et al. Conformational properties of central nervous system active thyrotropin releasing hormone analogues: probing structure-activity relationships at the molecular level. J Med Chem. 1985 Jan;28 (1) :125-37. |[2]Zhang WJ, et al. Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues. J Am Chem Soc. 2003 Feb 5;125 (5) :1221-35.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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