[Phe2]-TRH

• Description:

  [Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin[1].

• UNSPSC:

  12352209

• Target:

  Thyroid Hormone Receptor

• Type:

  Peptides

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/phe2-trh.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H]1CCC(N1)=O)N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N)=O)=O

• Molecular Formula:

  C19H24N4O4

• Molecular Weight:

  372.42

• References & Citations:

  [1]Eckle E, et al. Conformational properties of central nervous system active thyrotropin releasing hormone analogues: probing structure-activity relationships at the molecular level. J Med Chem. 1985 Jan;28 (1) :125-37. |[2]Zhang WJ, et al. Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues. J Am Chem Soc. 2003 Feb 5;125 (5) :1221-35.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [34783-35-2]