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Optineurin/OPTN Rabbit Polyclonal Antibody

CAT: 0013-GTR17688960Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17688960Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-Optineurin/OPTN Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Name Alternative
Optineurin; E3-14.7K-interacting protein; FIP-2; Huntingtin yeast partner L; Huntingtin-interacting protein 7; HIP-7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; TFIIIA-IntP; OPTN; FIP2, GLC1E, HIP7, HYPL, NRP
UniProt
Q96CV9
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human Optineurin recombinant protein (Position: R241-I577) . Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse and rat Optineurin.
Target
Optineurin
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
Form
Lyophilized
Molecular Weight
75 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, IHC, WB
Host or Source
Rabbit
Preservative
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Isotype
Rabbit IgG

UniProtKB · Q96CV9

Optineurin

OPTN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96CV9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
OPTN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KP00, D3DRS4, D3DRS8, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Amyotrophic lateral sclerosisDisease variantGlaucomaNeurodegeneration

Biological process

AutophagyHost-virus interactionImmunityInnate immunity

Domain

Coiled coilZinc-finger

Cellular component

CytoplasmCytoplasmic vesicleEndosomeGolgi apparatus

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

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