Vapendavir-d5
CAT:
804-HY-106254S-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Vapendavir-d5
- CAS Number: 2738376-73-1
- UNSPSC Description: Vapendavir-d5 is the deuterium labeled Vapendavir. Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
- Target Antigen: Enterovirus; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Anti-infection;Others
- Field of Research: Infection
- Solubility: 10 mM in DMSO
- Smiles: [2H]C([2H])([2H])C([2H])([2H])OC1=NOC2=CC(OCCC3CCN(C4=CC=C(N=N4)C)CC3)=CC=C12
- Molecular Weight: 387.49
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.|[3]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported