Vapendavir

• Description :

  Vapendavir (BTA798) is a potent enteroviral capsid binder (CB) . Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

• Product Name Alternative :

  BTA798

• UNSPSC :

  12352005

• Target :

  Enterovirus

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/vapendavir.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12

• Molecular Formula :

  C21H26N4O3

• Molecular Weight :

  382.46

• References & Citations :

  [1]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58 (11) :6990-2.|[2]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59 (12) :7782-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Citation 01 :

  ACS Infect Dis. 2020 May 8;6 (5) :882-890.|SSRN. 2024 Apr 19.|Eur J Med Chem. 2025 Feb 14:288:117395.|Norwegian University of Science and Technology. 2023 May.

• CAS Number :

  [439085-51-5]