Vapendavir

• Description:

  Vapendavir (BTA798) is a potent enteroviral capsid binder (CB) . Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

• Product Name Alternative:

  BTA798

• UNSPSC:

  12352005

• Target:

  Enterovirus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/vapendavir.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12

• Molecular Formula:

  C21H26N4O3

• Molecular Weight:

  382.46

• References & Citations:

  [1]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58 (11) :6990-2.|[2]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59 (12) :7782-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Citation 01:

  ACS Infect Dis. 2020 May 8;6 (5) :882-890.|SSRN. 2024 Apr 19.|Eur J Med Chem. 2025 Feb 14:288:117395.|Norwegian University of Science and Technology. 2023 May.

• CAS Number:

  [439085-51-5]