Z-Ile-Leu-aldehyde
CAT:
804-HY-12465-04
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Z-Ile-Leu-aldehyde
- Product Name Alternative: Z-IL-CHO; GSI-XII; γ-Secretase inhibitor XII
- CAS Number: 161710-10-7
- UNSPSC Description: Z-Ile-Leu-aldehyde (Z-IL-CHO) is a potent and competitive peptide aldehyde inhibitor of γ-secretase and notch[1][2].
- Target Antigen: Apoptosis; Notch; γ-secretase
- Type: Reference compound
- Related Pathways: Apoptosis;Neuronal Signaling;Stem Cell/Wnt
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Z-Ile-Leu-aldehyde.html
- Purity: 98.0
- Solubility: DMSO : ≥ 41 mg/mL
- Smiles: O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@H](C=O)CC(C)C)=O)[C@@H](C)CC
- Molecular Weight: 362.46
- References & Citations: [1]Reem Suleiman, et al. The Role Of Notch In Th17 Differentiation. University of Massachusetts Amherst. 9-2013.|[2]Schwarzer R, et al. Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model. Blood Cancer J. 2014 Jun 13;4:e217.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported