Z-Leu-Leu-Leu-AMC

Z-Leu-Leu-Leu-AMC

• CAS Number: 152015-61-7
• UNSPSC Description: Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].
• Target Antigen: Proteasome
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/z-leu-leu-leu-amc.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1=CC=C(NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)C=C1O3)=CC3=O
• Molecular Weight: 648.79
• References & Citations: [1]McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported