Z-Leu-Leu-Leu-AMC

• UNSPSC Description:

  Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].

• Target Antigen:

  Proteasome

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/z-leu-leu-leu-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)C=C1O3)=CC3=O

• Molecular Weight:

  648.79

• References & Citations:

  [1]McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  152015-61-7