MSC-4106
CAT:
804-HY-147208-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MSC-4106
- CAS Number: 2738542-58-8
- UNSPSC Description: MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model[1].
- Target Antigen: YAP
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/msc-4106.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC2=C(N(C3=CC=C(C(F)(F)F)C=C3)C4=NN(C)C=C42)C=C1)O
- Molecular Weight: 359.30
- References & Citations: [1]Timo Heinrich, et al. Optimization of TEAD P-site binding fragment hit into in vivo active lead MSC-4106. J. Med. Chem. 2022, 65, 13, 9206–9229.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported