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Tucidinostat

CAT: 0026-B3059-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B3059-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tucidinostat is an inhibitor of histone deacetylases (HDACs) with IC₅₀ values of 95 nM, 160 nM, 67 nM and 78 nM for HDAC1, HDAC2, HDAC3 and HDAC10 respectively. It shows potent antitumor activity. It inhibits several human derived tumor cell lines, such as HL-60, U2OS, LNCaP with GI₅₀ values of 0.4-40 μM but has no effect on the growth of non-cancerous CCC-HEK human fetal kidney or CCC-HEL human liver cells. It (12.5-50 mg/kg, p.o) reduces tumor growth in mouse xenograft models.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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