Products for Research Use Only

LLY-283

CAT: 0026-B2749-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-B2749-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LLY-283 is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 = 22 nM). It is selective for PRMT5 over a panel of 32 methyltransferases, including PRMT4, -6, and -7 at 1 μM. LLY-283 reduces proliferation of various breast, gastric, hematological, lung, skin, and ovarian cancer cell lines (IC50s = 3-30 nM).
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months