Products for Research Use Only

LLY-507

CAT: 0026-B1111-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1111-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LLY-507 is a potent, cell-permeable, small molecule inhibitor of SMYD2 (IC₅₀ = 15 nM), a lysine N-methyltransferase.  It has been shown to inhibit p53 lysine monomethylation in KYSE-150 esophageal squamous cell carcinoma cells stably expressing SMYD2 with an IC₅₀ value of 0.6 µM. LLY-507 is >100-fold selective for SMYD2 over a panel of 27 protein methyltransferases and non-methyltransferase targets.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months