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Ditolylguanidine

CAT: 0026-B3044-100Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0026-B3044-100Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ditolylguanidine is a sigma receptor (σR) agonist with neuroprotective activity. It shows Kd values of 21.9 nM and 57.4 nM for σ2 and σ1 receptor respectively. Combined treatment with Ditolylguanidine (5 mg/kg) and memantine induces antidepressant-like effect in rats. Sigma receptor modulators are predicted to show activity against SARS-Cov-2, based on viral assay screens and interaction of the SARS-CoV-2 proteins Nsp6 and Orf9c with sigma receptors.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months