LM22B-10

CAT: 0026-B3018-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B3018-25Size:25 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LM22B-10 is an activator of Tropomyosin-receptor kinase neurotrophin receptors TrkB and TrkC. It binds to TrkB and TrkC in a dose-dependent manner at concentrations of 250 nM-2000 nM. It increases cell survival and accelerates neurite outgrowth. LM22B-10 supports substantial early neurite outgrowth in the presence of inhibiting glycoproteins. In aged mice, it (50 mg/kg/day i.p. in combination with an intranasal dose of 5 mg/kg/day for 30 days) activates hippocampal and striatal TrkB and TrkC, their downstream signaling and increases hippocampal dendritic spine density.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

Popular Products